The Werewolf of London (1935)

Synopsis
Originally intended as a vehicle for Boris Karloff and Bela Lugosi, this Universal production predated The Wolf Man by six years, but failed to whip up audience enthusiasm for the monster popularized by Lon Chaney, Jr. in the studio's later classic. Henry Hull stars as botanist Dr. Glendon, whose foray through Tibet in search of a rare night-blooming "marifasa lupina" ends when he is savagely attacked by man-beast Yogami (Warner Oland). Recovering back in London, Glendon begins to undergo the hideous transformation into a wolf-like monster at the next full moon (courtesy of makeup work by Jack Pierce), and learns that only the bloom of the marifasa can reverse his condition -- a cure which is currently being sought by yet another lycanthropic predator. ~ Cavett Binion, All Movie Guide