Doglike Manticore refugee Joshua (
Kevin Durand) has befriended Annie Fisher (
Kandyse McClure), a blind woman who does not fear him because she cannot see him. Meanwhile, public hostility against Joshua and his fellow transgens is fueled by White (Martin Cummins) and Mrs. Morehead (Gabrielle Rose). The hysteria reaches a fever pitch when it appears that Joshua has kidnapped Annie. To save her fellow transgen, Max (
Jessica Alba) may have to break her vow to avoid Logan (
Michael Weatherly) -- even if it means infecting Logan with her deadly virus. ~ Hal Erickson, All Movie Guide